Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799402 | 1.00 | PTGS2 (0.47) | PTGS2PTGS1TSHRMEN1KMT2A | |
| SCHEMBL5798168 | 0.93 | PTGS2 (0.45) | PTGS2PTGS1TSHR | |
| SCHEMBL5798165 | 0.93 | PTGS2 (0.45) | PTGS2PTGS1TSHR | |
| SCHEMBL5800568 | 0.91 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL5800571 | 0.91 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL5800975 | 0.90 | PTGS2 (0.45) | PTGS2PTGS1TSHR | |
| SCHEMBL5814024 | 0.89 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL5797049 | 0.89 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL5797534 | 0.89 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL5797216 | 0.89 | PTGS2 (0.44) | PTGS2PTGS1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |