Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5822684 | 0.92 | PTGS2 (0.43) | PTGS2PTGS1 | |
| SCHEMBL6424972 | 0.90 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL6424278 | 0.90 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL6426910 | 0.90 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL6424664 | 0.90 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL5797391 | 0.90 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL6423962 | 0.90 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL6426692 | 0.90 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL5799402 | 0.90 | PTGS2 (0.47) | PTGS2PTGS1TSHR | |
| SCHEMBL5799396 | 0.90 | PTGS2 (0.47) | PTGS2PTGS1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |