Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | SKP1 | P63208 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465144 | 0.81 | KMT2A (0.48) | KMT2AL3MBTL1USP30KDM1AMAOB | |
| SCHEMBL27304124 | 0.77 | KCNA3 (0.53) | KMT2AL3MBTL1USP30KDM1AMAOB | |
| SCHEMBL18465167 | 0.76 | USP30 (0.53) | KMT2AL3MBTL1USP30KDM1AMAOB | |
| SCHEMBL20253879 | 0.75 | KMT2A (0.46) | KMT2ASCN1ASCN2ASCN3AMEN1 | |
| SCHEMBL21335570 | 0.74 | KDM1A (0.41) | KMT2AL3MBTL1USP30KDM1AMAOB | |
| SCHEMBL7474525 | 0.73 | MAPT (0.41) | KMT2AL3MBTL1KDM1AMAOBKCNA3 | |
| SCHEMBL27989405 | 0.73 | CHRNA7 (0.46) | KMT2AL3MBTL1SCN1ASCN2ASCN3A | |
| SCHEMBL21726751 | 0.73 | KMT2A (0.40) | KMT2AL3MBTL1USP30KDM1AMAOB | |
| SCHEMBL27978282 | 0.73 | FKBP1A (0.52) | KMT2AL3MBTL1KDM4ETSHR | |
| SCHEMBL4703541 | 0.72 | USP30 (0.56) | KMT2AL3MBTL1USP30KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664025-A1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | AstraZeneca AB (SE) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005026149-A1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2005-03-24 | — | — | WO | disclosed |