Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465181 | 0.87 | ALDH1A1 (0.46) | L3MBTL1GAAEPHX2ALDH1A1 | |
| SCHEMBL8484888 | 0.82 | BTK (0.49) | KMT2AL3MBTL1DRD2GAAHPGD | |
| SCHEMBL27978282 | 0.81 | FKBP1A (0.52) | KMT2AL3MBTL1 | |
| SCHEMBL4703541 | 0.81 | USP30 (0.56) | KMT2AL3MBTL1NAMPTHPGDKDM1A | |
| SCHEMBL5799516 | 0.81 | KMT2A (0.44) | KMT2AL3MBTL1NAMPTDRD2KDM1A | |
| SCHEMBL7470151 | 0.80 | HPGD (0.49) | KMT2AHPGDALDH1A1 | |
| SCHEMBL4616517 | 0.79 | NAMPT (0.69) | KMT2AL3MBTL1NAMPTDRD2KDM1A | |
| SCHEMBL30509621 | 0.78 | KDM4E (0.52) | KMT2AGAAUSP30EPHX1 | |
| SCHEMBL6172743 | 0.78 | L3MBTL1 (0.51) | KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL28961482 | 0.78 | USP30 (0.54) | KMT2AMEN1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |