Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799023 | 0.92 | GLO1 (0.57) | GLO1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5799017 | 0.92 | GLO1 (0.57) | GLO1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5798881 | 0.86 | GLO1 (0.60) | GLO1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5819439 | 0.84 | GLO1 (0.49) | GLO1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5798959 | 0.84 | GLO1 (0.49) | GLO1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5807900 | 0.83 | GLO1 (0.48) | GLO1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5807897 | 0.83 | GLO1 (0.48) | GLO1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5796789 | 0.77 | MAPT (0.58) | GLO1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28623538 | 0.77 | CYP1A2 (0.73) | GLO1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5814003 | 0.75 | KDM4E (0.46) | GLO1MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |