Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5813996 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1PKMMAPTMEN1 | |
| SCHEMBL5807897 | 0.93 | GLO1 (0.48) | KDM4EALDH1A1PKMMAPTMEN1 | |
| SCHEMBL5807900 | 0.93 | GLO1 (0.48) | KDM4EALDH1A1PKMMAPTMEN1 | |
| SCHEMBL5797406 | 0.92 | KDM4E (0.45) | KDM4EALDH1A1PKMMAPTMEN1 | |
| SCHEMBL5797405 | 0.92 | KDM4E (0.45) | KDM4EALDH1A1PKMMAPTMEN1 | |
| SCHEMBL5795687 | 0.84 | CYP1A2 (0.47) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5796791 | 0.80 | P2RX3 (0.47) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5798959 | 0.79 | GLO1 (0.49) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5819439 | 0.79 | GLO1 (0.49) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5797809 | 0.78 | ALDH1A1 (0.43) | KDM4EALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |