Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 12/20 | 0.41 |
| ▸ | BCL2 | P10415 | 2/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BAD | Q92934 | 2/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | EEF2K | O00418 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PAK4 | O96013 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | MARK3 | P27448 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5823605 | 0.88 | MCL1 (0.41) | MCL1BCL2BCL2L1BADPIN1 | |
| SCHEMBL5799061 | 0.83 | SCD (0.41) | MCL1BCL2BCL2L1BADPIN1 | |
| SCHEMBL5808425 | 0.81 | MAPT (0.42) | MCL1PIN1KMT2AMEN1MAPT | |
| SCHEMBL5799794 | 0.79 | MCL1 (0.41) | MCL1BCL2BCL2L1BADPIN1 | |
| SCHEMBL5813649 | 0.78 | MRGPRX4 (0.43) | MCL1BCL2BCL2L1BADPIN1 | |
| SCHEMBL5797679 | 0.77 | KMT2A (0.41) | MCL1BCL2BCL2L1BADPIN1 | |
| SCHEMBL5812469 | 0.77 | KMT2A (0.39) | MCL1PIN1KMT2AMEN1MAPT | |
| SCHEMBL5810719 | 0.72 | MAPT (0.41) | MCL1BCL2BCL2L1BADKMT2A | |
| SCHEMBL5810724 | 0.72 | MAPT (0.41) | MCL1BCL2BCL2L1BADKMT2A | |
| SCHEMBL5808413 | 0.72 | PIN1 (0.42) | MCL1PIN1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |