Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 9/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | BAD | Q92934 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5810719 | 0.93 | MAPT (0.41) | MCL1BCL2BCL2L1BADBCHE | |
| SCHEMBL5810724 | 0.93 | MAPT (0.41) | MCL1BCL2BCL2L1BADBCHE | |
| SCHEMBL5823606 | 0.88 | PIN1 (0.40) | MCL1BCL2BCL2L1BADMAPT | |
| SCHEMBL5799066 | 0.83 | KMT2A (0.47) | MCL1MAPTKMT2AMEN1LMNA | |
| SCHEMBL5808243 | 0.80 | P2RX3 (0.42) | MCL1BCL2BCL2L1BADMAPT | |
| SCHEMBL5808246 | 0.80 | P2RX3 (0.42) | MCL1BCL2BCL2L1BADMAPT | |
| SCHEMBL5808427 | 0.80 | MAPT (0.48) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL5808433 | 0.80 | MAPT (0.48) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL5799790 | 0.79 | MCL1 (0.41) | MCL1BCL2BCL2L1BADMAPT | |
| SCHEMBL5822007 | 0.78 | PIN1 (0.44) | MCL1BCL2L1MAPTPIN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |