Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PTPRF | P10586 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577227 | 0.84 | MEN1 (0.46) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9543049 | 0.75 | MEN1 (0.43) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2747548 | 0.74 | MEN1 (0.50) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8268827 | 0.72 | SLC1A1 (0.63) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7141466 | 0.71 | CYP1A2 (0.67) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3091161 | 0.70 | TSHR (0.53) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10436410 | 0.69 | CPA1 (0.57) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8102675 | 0.69 | GSK3B (0.53) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6810144 | 0.69 | KMT2A (0.52) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6810226 | 0.69 | KMT2A (0.52) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006047251-A2 | 3-ALKYLARYL ASPARTATE COMPOUNDS AND THEIR USE FOR SELECTIVE ENHANCEMENT OF SYNAPTIC TRANSMISSION | THE UNIVERSITY OF MONTANA (US) | 2006-05-04 | — | — | WO | disclosed |