Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6810226 | 1.00 | KMT2A (0.52) | KMT2AMEN1NPC1TP53RAB9A | |
| SCHEMBL7429456 | 0.94 | NPC1 (0.53) | KMT2AMEN1NPC1TP53RAB9A | |
| SCHEMBL27581401 | 0.88 | ESR1 (0.54) | KMT2AMEN1NPC1TP53RAB9A | |
| SCHEMBL2658881 | 0.83 | ALDH1A1 (0.48) | KMT2AMEN1NPC1TP53RAB9A | |
| Toluene SCHEMBL28163126 | 0.83 | RAB9A (0.45) | KMT2AMEN1NPC1TP53RAB9A | |
| SCHEMBL6625969 | 0.82 | EPHX1 (0.69) | KMT2AMEN1NPC1TP53RAB9A | |
| SCHEMBL27581400 | 0.82 | NPC1 (0.54) | KMT2AMEN1NPC1TP53RAB9A | |
| SCHEMBL11262646 | 0.82 | CYP1A2 (0.54) | KMT2AMEN1NPC1TP53RAB9A | |
| SCHEMBL599399 | 0.81 | EPHX1 (0.71) | EPHX1CYP1A2CYP2C19CPA1 | |
| SCHEMBL67234 | 0.81 | EPHX1 (0.71) | EPHX1CYP1A2CYP2C19CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9718763-B2 | Catalytic ester decarbonylation | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2017-08-01 | — | — | US | disclosed |
| US-20160194276-A1 | CATALYTIC ESTER DECARBONYLATION | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2016-07-07 | — | — | US | disclosed |
| US-20040014161-A1 | pH-indicator based assay for selective enzymes | THERMOGEN, INC. | 2004-01-22 | — | — | US | disclosed |
| US-20020177180-A1 | pH-indicator based assay for selective enzymes | THERMOGEN, INC. | 2002-11-28 | — | — | US | disclosed |
| EP-1090139-A1 | PH-INDICATOR BASED ASSAY FOR SELECTIVE ENZYMES | Thermogen, Inc. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067420-A1 | pH-INDICATOR BASED ASSAY FOR SELECTIVE ENZYMES | THERMOGEN, INC. (US) | 1999-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194276-A1 | CATALYTIC ESTER DECARBONYLATION | DECR1, C1S, CBR3 | KMT2A 1979/4885MEN1 1360/4885NPC1 2770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.