Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 2/20 | 0.45 |
| ▸ | ACE | P12821 | 4/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335398 | 0.88 | MAPT (0.51) | SLC7A5LDHAACEMMECPA1 | |
| SCHEMBL2828887 | 0.87 | LDHA (0.44) | LDHAMMEMAPT | |
| SCHEMBL11274903 | 0.87 | LDHA (0.44) | LDHAACEMMECPA1ACE2 | |
| SCHEMBL2672622 | 0.87 | PPARG (0.47) | LDHAMAPTSLC6A2 | |
| SCHEMBL2672698 | 0.85 | LDHA (0.67) | LDHAMAPT | |
| SCHEMBL2672561 | 0.84 | CYP19A1 (0.46) | LDHAMAPT | |
| SCHEMBL2672529 | 0.83 | MAOB (0.44) | LDHAACEMAPT | |
| SCHEMBL2672732 | 0.82 | MEN1 (0.46) | LDHAMAPT | |
| SCHEMBL5802386 | 0.81 | MMP8 (0.56) | SLC7A5LDHAESR1ESR2FOLH1 | |
| SCHEMBL3963049 | 0.77 | PPARA (0.48) | SLC7A5ACEMMECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006057505-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPARϜ AND PPARα, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2006-06-01 | — | — | WO | disclosed |