Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800266 | 1.00 | TSHR (0.39) | TSHRPTGS2ABCB11AKR1C3AKR1C2 | |
| SCHEMBL5800360 | 0.94 | PTGS2 (0.38) | TSHRPTGS2ABCB11AKR1C3AKR1C2 | |
| SCHEMBL5800364 | 0.94 | PTGS2 (0.38) | TSHRPTGS2ABCB11AKR1C3AKR1C2 | |
| SCHEMBL5808998 | 0.93 | PTGS2 (0.35) | TSHRPTGS2AKR1C3AKR1C2PSEN1 | |
| SCHEMBL5808994 | 0.93 | PTGS2 (0.35) | TSHRPTGS2AKR1C3AKR1C2PSEN1 | |
| SCHEMBL5798228 | 0.92 | PTGS2 (0.40) | TSHRPTGS2 | |
| SCHEMBL5560484 | 0.91 | TSHR (0.35) | TSHRPTGS2ABCB11AKR1C3AKR1C2 | |
| SCHEMBL5801230 | 0.90 | PTGS2 (0.36) | TSHRPTGS2ABCB11AKR1C3AKR1C2 | |
| SCHEMBL5801225 | 0.90 | PTGS2 (0.36) | TSHRPTGS2ABCB11AKR1C3AKR1C2 | |
| SCHEMBL5808521 | 0.90 | APP (0.37) | TSHRPTGS2ABCB11AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |