Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5822573 | 0.94 | APP (0.37) | APPPTGS2 | |
| SCHEMBL5555390 | 0.90 | APP (0.40) | APPPTGS2 | |
| SCHEMBL5812636 | 0.90 | APP (0.38) | APPPTGS2 | |
| SCHEMBL5799882 | 0.90 | TSHR (0.39) | TSHRLMNAHPGDPTGS2 | |
| SCHEMBL5797833 | 0.90 | PTGS2 (0.34) | TSHRLMNAHPGDPTGS2HSD11B1 | |
| SCHEMBL5799881 | 0.90 | TSHR (0.39) | TSHRLMNAHPGDPTGS2 | |
| SCHEMBL5797831 | 0.90 | PTGS2 (0.34) | TSHRLMNAHPGDPTGS2HSD11B1 | |
| SCHEMBL5808521 | 0.89 | APP (0.37) | APPTSHRHPGDPTGS2 | |
| SCHEMBL5554159 | 0.87 | PSEN1 (0.38) | APPTSHRHPGDPTGS2 | |
| SCHEMBL5554154 | 0.87 | PSEN1 (0.38) | APPTSHRHPGDPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |