Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799881 | 1.00 | TSHR (0.39) | TSHRLMNAMGLLPTGS2KMT2A | |
| SCHEMBL5797881 | 0.94 | PTGS2 (0.36) | TSHRLMNAPTGS2KMT2AHPGD | |
| SCHEMBL5797882 | 0.94 | PTGS2 (0.36) | TSHRLMNAPTGS2KMT2AHPGD | |
| SCHEMBL5801013 | 0.92 | ESR1 (0.38) | TSHRPTGS2 | |
| SCHEMBL5801009 | 0.92 | ESR1 (0.38) | TSHRPTGS2 | |
| SCHEMBL5798904 | 0.91 | TSHR (0.35) | TSHRLMNAMGLLPTGS2KMT2A | |
| SCHEMBL5797833 | 0.90 | PTGS2 (0.34) | TSHRLMNAPTGS2HPGD | |
| SCHEMBL5797831 | 0.90 | PTGS2 (0.34) | TSHRLMNAPTGS2HPGD | |
| SCHEMBL5813216 | 0.90 | ALDH1A1 (0.35) | PTGS2KMT2AALDH1A1MEN1 | |
| SCHEMBL5797277 | 0.90 | PTGS2 (0.42) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |