Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800522 | 1.00 | LMNA (0.38) | LMNAELANEAKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL5797107 | 0.91 | LMNA (0.40) | LMNAELANEAKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL5801105 | 0.90 | CNR1 (0.36) | ELANEALDH1A1SMN1; SMN2MEN1NPC1 | |
| SCHEMBL5801111 | 0.90 | CNR1 (0.36) | ELANEALDH1A1SMN1; SMN2MEN1NPC1 | |
| SCHEMBL5800983 | 0.90 | LMNA (0.45) | LMNAELANEAKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL5800985 | 0.90 | LMNA (0.45) | LMNAELANEAKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL5553843 | 0.89 | LMNA (0.38) | LMNAELANEAKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL5557670 | 0.88 | AKR1C3 (0.40) | LMNAAKR1C3AKR1C2ALDH1A1PIK3CD | |
| SCHEMBL5554693 | 0.88 | AKR1C3 (0.40) | LMNAAKR1C3AKR1C2ALDH1A1PIK3CD | |
| SCHEMBL5547108 | 0.88 | AKR1C3 (0.40) | LMNAAKR1C3AKR1C2ALDH1A1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |