Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800983 | 1.00 | LMNA (0.45) | LMNAELANEAKR1C3AKR1C2ADRB2 | |
| SCHEMBL5798014 | 0.93 | LMNA (0.41) | LMNAELANEAKR1C3AKR1C2ADRB2 | |
| SCHEMBL5798016 | 0.93 | LMNA (0.41) | LMNAELANEAKR1C3AKR1C2ADRB2 | |
| SCHEMBL5798594 | 0.92 | LMNA (0.39) | LMNAELANEAKR1C3AKR1C2ADRB2 | |
| SCHEMBL5797107 | 0.91 | LMNA (0.40) | LMNAELANEAKR1C3AKR1C2ADRB2 | |
| SCHEMBL5798158 | 0.90 | ELANE (0.41) | LMNAELANESMN1; SMN2MAPTHPGD | |
| SCHEMBL5800522 | 0.90 | LMNA (0.38) | LMNAELANEAKR1C3AKR1C2ADRB2 | |
| SCHEMBL5800520 | 0.90 | LMNA (0.38) | LMNAELANEAKR1C3AKR1C2ADRB2 | |
| SCHEMBL5553843 | 0.89 | LMNA (0.38) | LMNAELANEAKR1C3AKR1C2ADRB2 | |
| SCHEMBL5547108 | 0.88 | AKR1C3 (0.40) | LMNAAKR1C3AKR1C2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |