Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11624332 | 0.87 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL27351137 | 0.86 | KDM4E (0.47) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL5801775 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL11622240 | 0.82 | TARBP2 (0.61) | ALDH1A1KDM4EHPGDKMT2AMAPT | |
| SCHEMBL8813501 | 0.77 | KDM4E (0.50) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL11620413 | 0.76 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL5098263 | 0.75 | KDM4E (0.63) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL6583843 | 0.74 | POLB (0.64) | ALDH1A1KDM4EHPGDKMT2AMAPT | |
| SCHEMBL14776632 | 0.74 | KDM4E (0.47) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL15007989 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006057503-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPARϜ AND PPARα, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2006-06-01 | — | — | WO | disclosed |