Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800639 | 0.83 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL11624332 | 0.82 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL11622240 | 0.80 | TARBP2 (0.61) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL27351137 | 0.79 | KDM4E (0.47) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL3093844 | 0.77 | TARBP2 (0.60) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL5098263 | 0.74 | KDM4E (0.63) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL7724076 | 0.73 | KDM4E (0.51) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL14776632 | 0.73 | KDM4E (0.47) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL8813501 | 0.73 | KDM4E (0.50) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL13740045 | 0.72 | TARBP2 (0.65) | ALDH1A1KDM4EHSD17B10MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006057503-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPARϜ AND PPARα, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2006-06-01 | — | — | WO | disclosed |