Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 8/20 | 0.47 |
| ▸ | FABP2 | P12104 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5157423 | 0.81 | PPARA (0.55) | PPARAKMT2ACYP2C19MEN1CYP1A2 | |
| SCHEMBL5822903 | 0.80 | ALDH1A1 (0.57) | PPARAKMT2ACYP2C19MEN1CYP1A2 | |
| SCHEMBL1046455 | 0.79 | ALDH1A1 (0.60) | PPARAKMT2ACYP2C19MEN1CYP1A2 | |
| SCHEMBL11939834 | 0.79 | ALDH1A1 (0.55) | PPARAKMT2ACYP2C19MEN1CYP1A2 | |
| SCHEMBL23871139 | 0.78 | PPARA (0.55) | PPARAKMT2ACYP2C19MEN1CYP1A2 | |
| SCHEMBL20659600 | 0.78 | PPARA (0.47) | PPARAKMT2ACYP2C19MEN1CYP1A2 | |
| SCHEMBL29195871 | 0.78 | ALDH1A1 (0.58) | PPARAKMT2ACYP2C19MEN1CYP1A2 | |
| SCHEMBL7994922 | 0.77 | KDM4E (0.49) | PPARAKMT2ACYP2C19MEN1CYP1A2 | |
| SCHEMBL5159180 | 0.75 | PPARA (0.52) | PPARAKMT2ACYP2C19MEN1CYP1A2 | |
| SCHEMBL11513032 | 0.75 | KMT2A (0.42) | KMT2AMEN1MAPTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006058199-A1 | METHODS OF MODULATING HIGH-DENSITY LIPOPROTEIN CHOLESTEROL LEVELS AND PHARMACEUTICAL FORMULATIONS FOR THE SAME | FAZIX CORPORATION (US) | 2006-06-01 | — | — | WO | disclosed |
| US-20060111346-A1 | Methods of modulating high-density lipoprotein cholesterol levels and pharmaceutical formulations for the same | FAZIX CORPORATION. | 2006-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111346-A1 | Methods of modulating high-density lipoprotein cholesterol levels and pharmaceutical formulations for the same | HDLBP, LDLR, CETP | PPARA 194/4885KMT2A 2359/4885CYP2C19 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.