Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 9/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | FABP2 | P12104 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1046455 | 0.86 | ALDH1A1 (0.60) | ALDH1A1KDM4EHSD17B10PPARAKMT2A | |
| SCHEMBL11939834 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KDM4EHSD17B10PPARAKMT2A | |
| SCHEMBL29195871 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KDM4EHSD17B10PPARAKMT2A | |
| SCHEMBL10907463 | 0.82 | KDM4E (0.53) | ALDH1A1KDM4EHSD17B10PPARAKMT2A | |
| SCHEMBL10715008 | 0.81 | PPARA (0.41) | ALDH1A1KDM4EHSD17B10PPARAKMT2A | |
| SCHEMBL5800645 | 0.80 | PPARA (0.55) | ALDH1A1KDM4EHSD17B10PPARAKMT2A | |
| SCHEMBL12804549 | 0.80 | PPARA (0.56) | ALDH1A1PPARAKMT2ACYP1A2CYP3A4 | |
| SCHEMBL24252065 | 0.79 | ALDH1A1 (0.41) | ALDH1A1KDM4EKMT2AMEN1CYP2C19 | |
| SCHEMBL11751450 | 0.78 | KMT2A (0.40) | ALDH1A1KDM4EKMT2AMEN1CYP2C19 | |
| SCHEMBL11823888 | 0.77 | KDM4E (0.55) | ALDH1A1KDM4EHSD17B10PPARAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006058199-A1 | METHODS OF MODULATING HIGH-DENSITY LIPOPROTEIN CHOLESTEROL LEVELS AND PHARMACEUTICAL FORMULATIONS FOR THE SAME | FAZIX CORPORATION (US) | 2006-06-01 | — | — | WO | disclosed |
| US-20060111346-A1 | Methods of modulating high-density lipoprotein cholesterol levels and pharmaceutical formulations for the same | FAZIX CORPORATION. | 2006-05-25 | — | — | US | disclosed |
| US-4826861-A | MEDICAL BACTERICIDES OR FUNGICIDES | ALBERT ROLAND, S.A. (FR) | 1989-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111346-A1 | Methods of modulating high-density lipoprotein cholesterol levels and pharmaceutical formulations for the same | HDLBP, LDLR, CETP | ALDH1A1 3198/4885KDM4E 2223/4885HSD17B10 457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.