Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 3/20 | 0.74 |
| ▸ | HTR6 | P50406 | 3/20 | 0.74 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.61 |
| ▸ | HTR7 | P34969 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HTR3A | P46098 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4244966 | 0.85 | HTR1D (1.00) | HTR1DHTR6TRPM8HSD17B10HTR7 | |
| Hydrochloric Acid SCHEMBL7433474 | 0.84 | HTR1D (0.97) | HTR1DHTR6TRPM8HSD17B10HTR7 | |
| SCHEMBL23181347 | 0.83 | TRPM8 (1.00) | HTR1DHTR6TRPM8HSD17B10HTR7 | |
| SCHEMBL29751588 | 0.83 | TRPM8 (1.00) | HTR1DHTR6TRPM8HSD17B10HTR7 | |
| Cyanide SCHEMBL28561862 | 0.82 | HTR1D (0.92) | HTR1DHTR6TRPM8HSD17B10HTR7 | |
| SCHEMBL18222556 | 0.81 | HTR1D (0.63) | HTR1DHTR6TRPM8HSD17B10HTR7 | |
| SCHEMBL6017242 | 0.79 | TRPM8 (0.68) | HTR1DHTR6TRPM8HSD17B10HTR7 | |
| SCHEMBL1320834 | 0.79 | HTR1D (0.67) | HTR1DHTR6TRPM8HSD17B10HTR7 | |
| SCHEMBL7886752 | 0.79 | HTR1D (0.71) | HTR1DHTR6TRPM8HSD17B10HTR7 | |
| SCHEMBL18235623 | 0.78 | HTR1D (0.59) | HTR1DHTR6TRPM8HSD17B10HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1693366-A1 | Selective 5-HT 6 receptor ligands | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2006-08-23 | — | — | EP | disclosed |