Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 4/20 | 1.00 |
| ▸ | HTR6 | P50406 | 4/20 | 1.00 |
| ▸ | HTR7 | P34969 | 3/20 | 0.70 |
| ▸ | HTR1A | P08908 | 2/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.70 |
| ▸ | HTR1E | P28566 | 1/20 | 0.70 |
| ▸ | HTR5A | P47898 | 1/20 | 0.70 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | HTR3A | P46098 | 1/20 | 0.64 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.62 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.62 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7433474 | 0.98 | HTR1D (0.97) | HTR1DHTR6HTR7HTR1ASLC6A2 | |
| Cyanide SCHEMBL28561862 | 0.96 | HTR1D (0.92) | HTR1DHTR6HTR7HTR1ASLC6A2 | |
| SCHEMBL7806663 | 0.90 | HTR1D (0.82) | HTR1DHTR6HTR7HTR1ASLC6A2 | |
| SCHEMBL8555235 | 0.86 | HTR1D (0.76) | HTR1DHTR6HTR7HTR1ASLC6A2 | |
| SCHEMBL5800700 | 0.85 | HTR1D (0.74) | HTR1DHTR6HTR7HTR1ASLC6A2 | |
| SCHEMBL7864871 | 0.85 | HTR1D (0.74) | HTR1DHTR6HTR7HTR1ASLC6A2 | |
| SCHEMBL4231080 | 0.85 | HTR1D (0.74) | HTR1DHTR6HTR7HTR1ASLC6A2 | |
| SCHEMBL8229569 | 0.84 | HTR6 (0.72) | HTR1DHTR6HTR7HTR1ASLC6A2 | |
| SCHEMBL8946961 | 0.84 | HTR6 (0.72) | HTR1DHTR6HTR7HTR1ASLC6A2 | |
| SCHEMBL11374190 | 0.83 | ALDH1A1 (0.78) | HTR1DHTR6HTR7HTR1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746340-A | Synthetic method of 5-methoxy-2-methyltryptamine | 上海易恩化学技术有限公司 | 2020-02-04 | — | — | CN | claimed |
| WO-2001095902-A1 | A COMPOSITION COMPRISING A COMBINATION OF RECEPTOR AGONISTS AND ANTAGONISTS | RESPIRATORIUS AB (SE) | 2001-12-20 | — | — | WO | claimed |
| WO-2025099444-A1 | N-Acetylserotonin (NAS) Analogues | Beckley Psytech Limited (GB) | 2025-05-15 | — | — | WO | disclosed |
| CN-115093410-B | Preparation method of beta-carboline compound | 南京工业大学 | 2023-09-26 | — | — | CN | disclosed |
| US-20230279000-A1 | PYRIDOPYRIMIDINE DERIVATIVES USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2023-09-07 | — | — | US | disclosed |
| EP-4110778-A1 | PYRIDOPYRIMIDINE DERIVATIVES USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2023-01-04 | — | — | EP | disclosed |
| CN-115244048-A | Pyridopyrimidine derivatives useful for modulating AhR signaling | 捷豹治疗有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-115093410-A | Preparation method of beta-carboline compound | 南京工业大学 | 2022-09-23 | — | — | CN | disclosed |
| CN-110746340-A | Synthetic method of 5-methoxy-2-methyltryptamine | 上海易恩化学技术有限公司 | 2020-02-04 | — | — | CN | disclosed |
| CN-110746340-A | Synthetic method of 5-methoxy-2-methyltryptamine | 上海易恩化学技术有限公司 | 2020-02-04 | — | — | CN | disclosed |
| CN-110746340-A | Synthetic method of 5-methoxy-2-methyltryptamine | 上海易恩化学技术有限公司 | 2020-02-04 | — | — | CN | disclosed |
| US-20020103383-A1 | Selective 5-HT6 receptor ligands | GLENNON RICHARD A (US) | 2002-08-01 | — | — | US | disclosed |
| EP-1225882-A1 | SELECTIVE COX-2 INHIBITORY NOVEL ESTERS FROM INDOLEALKANOLS AND NOVEL AMIDES FROM INDOLEALKYLAMINES | Vanderbilt University (US) | 2002-07-31 | — | — | EP | disclosed |
| US-6403808-B1 | TREATING MENTAL DISORDERS | VIRGINIA COMMONWEALTH UNIVERSITY | 2002-06-11 | — | — | US | disclosed |
| EP-1149078-A1 | SELECTIVE 5-HT 6? RECEPTOR LIGANDS | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2001-10-31 | — | — | EP | disclosed |
| US-6306890-B1 | COMPOUNDS FOR INHIBITING CYCLOOXYGENASE | VANDERBILT UNIVERSITY | 2001-10-23 | — | — | US | disclosed |
| WO-2001015686-A1 | SELECTIVE COX-2 INHIBITORY NOVEL ESTERS FROM INDOLEALKANOLS AND NOVEL AMIDES FROM INDOLEALKYLAMINES | VANDERBILT UNIVERSITY (US) | 2001-03-08 | — | — | WO | disclosed |
| US-6187805-B1 | TREATING CONDITION FOR WHICH SELECTIVE AGONISM OR ANTAGONISM OF 5-HT-6 RECEPTORS IS INDICATED BY ADMINISTERING COMPOUNDS SUCH AS N,N-DIMETHYL 2-(1-(BENZENESULPHONYL)-5-METHOXY-1H-INDOL-3-YL)ETHYLAMINE | MERCK SHARP & DOHME LTD. (GB) | 2001-02-13 | — | — | US | disclosed |
| WO-2000034242-A1 | SELECTIVE 5-HT6 RECEPTOR LIGANDS | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2000-06-15 | — | — | WO | disclosed |
| US-5552428-A | ANTIARRHYTHMIA AGENTS FOR CARDIOVASCULAR DISORDERS USING MELATONIN DERIVATIVES | INSTITUTO FARMACOLOGICO LOMBARDO-IFLO, S.A.S. (IT) | 1996-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230279000-A1 | PYRIDOPYRIMIDINE DERIVATIVES USEFUL IN MODULATION OF AHR SIGNALLING | AHR, ARNT, PAH | HTR1D 714/4885HTR6 92/4885HTR7 465/4885 |
| US-20020103383-A1 | Selective 5-HT6 receptor ligands | HTR6, HTR4, HTR5A | HTR1D 16/4885HTR6 1/4885HTR7 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.