⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4910735 | 0.79 | — | — | |
| SCHEMBL14996062 | 0.71 | DNM1 (0.30) | — | |
| SCHEMBL1043900 | 0.71 | — | — | |
| SCHEMBL22472345 | 0.71 | FDPS (0.40) | — | |
| SCHEMBL13148931 | 0.69 | — | — | |
| SCHEMBL19598776 | 0.69 | — | — | |
| SCHEMBL12725369 | 0.69 | SLC2A1 (0.36) | — | |
| SCHEMBL19559978 | 0.67 | — | — | |
| SCHEMBL17520206 | 0.67 | — | — | |
| SCHEMBL22327228 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1631542-A1 | BICYCLIC COMPOUNDS HAVING BRADYKININ RECEPTORS AFFINITY AND PHARMACEUTICAL COMPOSITIONS THEREOF | Amgen, Inc. (US) | 2006-03-08 | — | — | EP | claimed |
| WO-2004092116-A1 | BICYCLIC COMPOUNDS HAVING BRADYKININ RECEPTORS AFFINITY AND PHARMACEUTICAL COMPOSITIONS THEREOF | AMGEN, INC. (US) | 2004-10-28 | — | — | WO | claimed |