Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800755 | 1.00 | PTGS2 (0.43) | PTGS2PTGS1AKR1C3AKR1C2LMNA | |
| SCHEMBL5801127 | 0.94 | PTGS2 (0.44) | PTGS2PTGS1 | |
| SCHEMBL5801130 | 0.94 | PTGS2 (0.44) | PTGS2PTGS1 | |
| SCHEMBL5799056 | 0.93 | PTGS2 (0.45) | PTGS2PTGS1AKR1C3AKR1C2LMNA | |
| SCHEMBL5799060 | 0.93 | PTGS2 (0.45) | PTGS2PTGS1AKR1C3AKR1C2LMNA | |
| SCHEMBL5820127 | 0.92 | PTGS2 (0.43) | PTGS2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL5797017 | 0.88 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL5797015 | 0.88 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL5799907 | 0.87 | LMNA (0.42) | PTGS2PTGS1AKR1C3AKR1C2LMNA | |
| SCHEMBL5799905 | 0.87 | LMNA (0.42) | PTGS2PTGS1AKR1C3AKR1C2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |