Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3563025 | 0.87 | CNR1 (0.55) | CNR1NPC1MEN1KMT2ALMNA | |
| SCHEMBL5803978 | 0.86 | CNR1 (0.48) | CNR1NPC1MEN1KMT2ALMNA | |
| SCHEMBL5801215 | 0.83 | CNR1 (0.60) | CNR1NPC1MEN1KMT2ALMNA | |
| SCHEMBL8264453 | 0.75 | F10 (0.46) | CNR1NPC1MEN1KMT2ALMNA | |
| SCHEMBL3564247 | 0.74 | CNR1 (0.52) | CNR1NPC1MEN1KMT2ALMNA | |
| SCHEMBL3557437 | 0.74 | CNR1 (0.52) | CNR1NPC1MEN1KMT2ALMNA | |
| SCHEMBL3563416 | 0.74 | FPR2 (0.57) | CNR1NPC1MEN1KMT2ALMNA | |
| SCHEMBL3569304 | 0.74 | CNR1 (0.52) | CNR1NPC1MEN1KMT2ALMNA | |
| SCHEMBL3560100 | 0.74 | PCTP (0.45) | CNR1NPC1MEN1KMT2ALMNA | |
| SCHEMBL5632770 | 0.74 | FPR2 (0.73) | CNR1NPC1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006063113-A2 | UREAS AS FACTOR XA INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2006-06-15 | — | — | WO | claimed |