SCHEMBL5801148 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	HSD11B1	P28845	1/20	0.38

▸	PTGS2	P35354	1/20	0.37

▸	PPARG	P37231	7/20	0.36

▸	PDE4B	Q07343	5/20	0.35

▸	PDE4D	Q08499	3/20	0.35

▸	PPARA	Q07869	2/20	0.35

▸	PTGDR2	Q9Y5Y4	1/20	0.34

▸	HRH3	Q9Y5N1	2/20	0.34

▸	EPHX2	P34913	1/20	0.34

▸	KCNQ3	O43525	1/20	0.34

▸	KCNQ2	O43526	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5800052	0.98	PTGS2 (0.39)	HSD11B1PTGS2PPARGPDE4BPDE4D
SCHEMBL5554125	0.88	PTGS2 (0.38)	HSD11B1PTGS2PPARGPDE4BPDE4D
SCHEMBL5559333	0.88	PTGS2 (0.43)	PTGS2
SCHEMBL5559074	0.87	PTGS2 (0.40)	HSD11B1PTGS2PPARGPDE4BPDE4D
SCHEMBL5798701	0.86	PTGS2 (0.45)	PTGS2
SCHEMBL5800015	0.86	PPARG (0.37)	PTGS2PPARGPPARAHRH3EPHX2
SCHEMBL5800017	0.86	PPARG (0.37)	PTGS2PPARGPPARAHRH3EPHX2
SCHEMBL5814051	0.86	HRH3 (0.39)	PTGS2PPARGPPARAHRH3EPHX2
SCHEMBL5814046	0.86	HRH3 (0.39)	PTGS2PPARGPPARAHRH3EPHX2
SCHEMBL5561287	0.86	PPARG (0.37)	PTGS2PPARGPPARAHRH3EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2006050120-A2	SYNTHESIS OF COX-2 AND FAAH INHIBITORS	MICROBIA, INC. (US)	2006-05-11	—	—	WO	disclosed