SCHEMBL5801259 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	PTGS2	P35354	5/20	0.44

▸	PTGS1	P23219	2/20	0.44

▸	ELANE	P08246	3/20	0.41

▸	CNR1	P21554	1/20	0.41

▸	CNR2	P34972	1/20	0.41

▸	MEN1	O00255	2/20	0.39

▸	KMT2A	Q03164	2/20	0.39

▸	POLB	P06746	1/20	0.39

▸	ALOX5	P09917	1/20	0.39

▸	PTGES	O14684	1/20	0.38

▸	MGLL	Q99685	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5800528	0.90	PTGS2 (0.47)	PTGS2PTGS1ELANECNR1CNR2
SCHEMBL5797008	0.90	PTGS2 (0.44)	PTGS2PTGS1ELANECNR1CNR2
SCHEMBL5800526	0.90	PTGS2 (0.47)	PTGS2PTGS1ELANECNR1CNR2
SCHEMBL5797009	0.90	PTGS2 (0.44)	PTGS2PTGS1ELANECNR1CNR2
SCHEMBL6424972	0.89	PTGS2 (0.56)	PTGS2PTGS1
SCHEMBL5797391	0.89	PTGS2 (0.56)	PTGS2PTGS1
SCHEMBL6424278	0.89	PTGS2 (0.56)	PTGS2PTGS1
SCHEMBL6426910	0.89	PTGS2 (0.56)	PTGS2PTGS1
SCHEMBL6423962	0.89	PTGS2 (0.56)	PTGS2PTGS1
SCHEMBL6424664	0.89	PTGS2 (0.56)	PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2006050120-A2	SYNTHESIS OF COX-2 AND FAAH INHIBITORS	MICROBIA, INC. (US)	2006-05-11	—	—	WO	disclosed