Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797009 | 1.00 | PTGS2 (0.44) | PTGS2PTGS1CNR1CNR2ELANE | |
| SCHEMBL5801259 | 0.90 | PTGS2 (0.44) | PTGS2PTGS1CNR1CNR2ELANE | |
| SCHEMBL5800528 | 0.90 | PTGS2 (0.47) | PTGS2PTGS1CNR1CNR2ELANE | |
| SCHEMBL5800526 | 0.90 | PTGS2 (0.47) | PTGS2PTGS1CNR1CNR2ELANE | |
| SCHEMBL5811244 | 0.89 | PTGS2 (0.44) | PTGS2PTGS1CNR1CNR2ELANE | |
| SCHEMBL5797636 | 0.89 | PTGS2 (0.57) | PTGS2PTGS1CNR2ALOX5 | |
| SCHEMBL5797635 | 0.89 | PTGS2 (0.57) | PTGS2PTGS1CNR2ALOX5 | |
| SCHEMBL5814637 | 0.88 | AKR1C3 (0.41) | PTGS2PTGS1ELANE | |
| SCHEMBL5814641 | 0.88 | AKR1C3 (0.41) | PTGS2PTGS1ELANE | |
| SCHEMBL5554423 | 0.87 | PTGS2 (0.50) | PTGS2PTGS1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |