Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2009205 | 0.93 | SMN1; SMN2 (0.51) | EPHX2NR1H4SMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL3604860 | 0.79 | RAB9A (0.49) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL2013987 | 0.79 | MAPT (0.49) | EPHX2NR1H4SMN1; SMN2CA12CA1 | |
| SCHEMBL3608658 | 0.78 | EPHX2 (0.62) | EPHX2NR1H4SMN1; SMN2CA12CA1 | |
| SCHEMBL2009888 | 0.78 | HDAC1 (0.55) | SMN1; SMN2MAPTNPC1RAB9AHDAC1 | |
| SCHEMBL16215508 | 0.78 | ALDH1A1 (0.55) | EPHX2NR1H4CA12CA1CA2 | |
| SCHEMBL19331732 | 0.78 | MAPT (0.51) | EPHX2NR1H4SMN1; SMN2MAPTSIGMAR1 | |
| SCHEMBL750357 | 0.78 | EPHX2 (0.58) | EPHX2NR1H4SMN1; SMN2CA12CA1 | |
| SCHEMBL2013045 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTNPC1RAB9AHDAC1 | |
| SCHEMBL1668544 | 0.77 | NR1H4 (0.76) | EPHX2NR1H4SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1677783-A2 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | Nicholas Piramal India Limited (IN) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005035495-A2 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2005-04-21 | — | — | WO | disclosed |