Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.72 |
| ▸ | NR1H4 | Q96RI1 | 8/20 | 0.72 |
| ▸ | PPARG | P37231 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800933 | 0.89 | EPHX2 (0.67) | EPHX2NR1H4PPARG | |
| SCHEMBL5823636 | 0.86 | EPHX2 (0.55) | EPHX2NR1H4PPARG | |
| SCHEMBL21990340 | 0.84 | EPHX2 (1.00) | EPHX2NR1H4PPARG | |
| SCHEMBL5801528 | 0.80 | EPHX2 (0.60) | EPHX2NR1H4 | |
| SCHEMBL22059490 | 0.77 | EPHX2 (0.75) | EPHX2NR1H4PPARG | |
| SCHEMBL22060060 | 0.76 | EPHX2 (0.66) | EPHX2NR1H4PPARG | |
| SCHEMBL5800996 | 0.75 | — | — | |
| SCHEMBL5715986 | 0.75 | EPHX2 (0.59) | EPHX2NR1H4PPARG | |
| SCHEMBL5803989 | 0.75 | — | — | |
| SCHEMBL22059489 | 0.74 | EPHX2 (0.82) | EPHX2NR1H4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006098554-A1 | NOVEL COMPOUNDS, ISOMER THEREOF OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2006-09-21 | — | — | WO | disclosed |