Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Ethylfuran SCHEMBL27945022 | 0.85 | TP53 (0.65) | POLBTDP1TP53MAPTALDH1A1 | |
| 2-Ethylfuran SCHEMBL29159372 | 0.84 | — | — | |
| 2-Ethylfuran SCHEMBL28496480 | 0.82 | — | — | |
| 2-Ethylfuran SCHEMBL27805720 | 0.82 | — | — | |
| SCHEMBL2266485 | 0.78 | POLB (0.47) | POLBTDP1TP53MAPTALDH1A1 | |
| 2-Ethylfuran SCHEMBL25423480 | 0.77 | RAB9A (0.44) | TDP1TP53MAPTALDH1A1KMT2A | |
| 2-Ethylfuran SCHEMBL28064288 | 0.77 | ALDH1A1 (0.44) | POLBTDP1MAPTALDH1A1KMT2A | |
| 2-Ethylfuran SCHEMBL28396261 | 0.75 | POLB (0.43) | POLBTDP1TP53MAPTALDH1A1 | |
| 2-Ethylfuran SCHEMBL27491633 | 0.75 | ALDH1A1 (0.56) | POLBTDP1MAPTALDH1A1RIPK1 | |
| 2-Ethylfuran SCHEMBL27782212 | 0.75 | ALDH1A1 (0.47) | POLBTDP1MAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534724-B1 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2006-03-08 | — | — | EP | disclosed |