Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 3/20 | 0.54 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798211 | 0.84 | CHEK1 (0.62) | CHEK1GPR35KMT2ALMNASMN1; SMN2 | |
| SCHEMBL22130973 | 0.79 | CYP11B1 (0.44) | CHEK1GPR35CYP11B1CYP11B2MEN1 | |
| SCHEMBL15907938 | 0.78 | CYP11B1 (0.48) | ALDH1A1CYP11B1CYP11B2MEN1CYP1A2 | |
| SCHEMBL12231011 | 0.77 | CYP11B1 (0.59) | ALDH1A1CYP11B1CYP11B2MEN1CYP1A2 | |
| SCHEMBL20222715 | 0.76 | CYP19A1 (0.44) | CHEK1GPR35KMT2AALDH1A1LMNA | |
| SCHEMBL23758529 | 0.76 | CHEK1 (0.56) | CHEK1GPR35KMT2AALDH1A1LMNA | |
| SCHEMBL2622517 | 0.75 | GPR3 (0.61) | CHEK1GPR35KMT2ALMNASMN1; SMN2 | |
| SCHEMBL20222583 | 0.75 | CYP19A1 (0.42) | CHEK1GPR35KMT2AALDH1A1LMNA | |
| SCHEMBL20222701 | 0.75 | CYP19A1 (0.49) | CHEK1GPR35KMT2AALDH1A1LMNA | |
| SCHEMBL20222697 | 0.74 | CYP19A1 (0.48) | CHEK1GPR35KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006060774-A2 | AGENTS THAT INHIBIT FLAVIVIRUS REPLICATION AND USES THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2006-06-08 | — | — | WO | disclosed |