Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 3/20 | 0.62 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | APAF1 | O14727 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | XBP1 | P17861 | 1/20 | 0.58 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | GALK1 | P51570 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2622517 | 0.91 | GPR3 (0.61) | CHEK1GPR35MEN1KMT2AL3MBTL1 | |
| SCHEMBL5798092 | 0.88 | CHEK1 (0.78) | CHEK1GPR35MEN1KMT2AL3MBTL1 | |
| SCHEMBL14353258 | 0.85 | GPR3 (0.50) | CHEK1GPR35MEN1KMT2AL3MBTL1 | |
| SCHEMBL903712 | 0.85 | GPR3 (0.50) | CHEK1GPR35MEN1KMT2AL3MBTL1 | |
| SCHEMBL23758529 | 0.85 | CHEK1 (0.56) | CHEK1GPR35MEN1KMT2AL3MBTL1 | |
| SCHEMBL5801828 | 0.84 | CHEK1 (0.54) | CHEK1GPR35MEN1KMT2AL3MBTL1 | |
| SCHEMBL20382194 | 0.82 | MAOA (0.51) | CHEK1GPR35MEN1KMT2AL3MBTL1 | |
| SCHEMBL5801776 | 0.82 | PTPRC (0.60) | CHEK1GPR35MEN1KMT2AL3MBTL1 | |
| SCHEMBL29368441 | 0.81 | GPR3 (0.75) | CHEK1GPR35MEN1KMT2AL3MBTL1 | |
| SCHEMBL472539 | 0.81 | GPR3 (0.75) | CHEK1GPR35MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006060774-A2 | AGENTS THAT INHIBIT FLAVIVIRUS REPLICATION AND USES THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2006-06-08 | — | — | WO | disclosed |