Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNPH1 | O43598 | 8/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.44 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.44 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440659 | 0.92 | P2RX3 (0.49) | P2RY1SRCP2RY2SMN1; SMN2P2RX1 | |
| SCHEMBL17515130 | 0.91 | DNPH1 (0.45) | DNPH1P2RY1TAS1R3TAS1R1PRKAB2 | |
| SCHEMBL3857490 | 0.89 | DNPH1 (0.43) | DNPH1P2RY1TAS1R3TAS1R1PRKAB2 | |
| SCHEMBL144526 | 0.86 | DNPH1 (0.46) | DNPH1P2RY1TAS1R3TAS1R1PRKAB2 | |
| SCHEMBL29465207 | 0.86 | DNPH1 (0.46) | DNPH1P2RY1TAS1R3TAS1R1PRKAB2 | |
| SCHEMBL8436321 | 0.85 | P2RX3 (0.49) | P2RY1SRCP2RY2SMN1; SMN2P2RX1 | |
| SCHEMBL3218602 | 0.84 | DNPH1 (0.44) | DNPH1P2RY1TAS1R3TAS1R1PRKAB2 | |
| SCHEMBL29974446 | 0.83 | PI4KA (0.40) | ADORA1SMN1; SMN2 | |
| SCHEMBL8441745 | 0.83 | P2RX3 (0.51) | P2RY1P2RY2P2RX1P2RX3P2RX4 | |
| SCHEMBL1085901 | 0.82 | P2RX1 (0.59) | P2RY1TRPM2SRCP2RY2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821692-B1 | IMMUNOPOTENTIATING INOSINE MONOPHOSPHATE 5'-NUCLEOTIDASE RESISTANT DERIVATIVES AND USES THEREOF | UNIV SOUTH FLORIDA (US) | 2006-01-11 | — | — | EP | claimed |