Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5802842 | 1.00 | TSHR (0.46) | TSHRCASP6NPSR1MEN1KMT2A | |
| SCHEMBL5802845 | 1.00 | TSHR (0.46) | TSHRCASP6NPSR1MEN1KMT2A | |
| SCHEMBL5802848 | 1.00 | TSHR (0.46) | TSHRCASP6NPSR1MEN1KMT2A | |
| SCHEMBL5801804 | 0.91 | LMNA (0.46) | NPSR1MEN1KMT2APOLBMAPT | |
| SCHEMBL5802478 | 0.91 | LMNA (0.46) | NPSR1MEN1KMT2APOLBMAPT | |
| SCHEMBL5806417 | 0.91 | LMNA (0.46) | NPSR1MEN1KMT2APOLBMAPT | |
| SCHEMBL5806329 | 0.89 | TSHR (0.47) | TSHRCASP6NPSR1MEN1KMT2A | |
| SCHEMBL5803635 | 0.89 | TSHR (0.47) | TSHRCASP6NPSR1MEN1KMT2A | |
| SCHEMBL5803960 | 0.89 | TSHR (0.47) | TSHRCASP6NPSR1MEN1KMT2A | |
| SCHEMBL5803638 | 0.89 | TSHR (0.47) | TSHRCASP6NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006082452-A1 | OPTICALLY ACTIVE DIARYL ACETIC ACID DERIVATIVES AND PROCESS FOR THEIR PREPARATION | SANOFI-AVENTIS (FR) | 2006-08-10 | — | — | WO | claimed |