Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5802478 | 1.00 | LMNA (0.46) | LMNAVCAM1TDP1MAPTPOLB | |
| SCHEMBL5806417 | 1.00 | LMNA (0.46) | LMNAVCAM1TDP1MAPTPOLB | |
| SCHEMBL5802848 | 0.91 | TSHR (0.46) | LMNATDP1MAPTPOLBHTT | |
| SCHEMBL5802842 | 0.91 | TSHR (0.46) | LMNATDP1MAPTPOLBHTT | |
| SCHEMBL5802845 | 0.91 | TSHR (0.46) | LMNATDP1MAPTPOLBHTT | |
| SCHEMBL5802840 | 0.91 | TSHR (0.46) | LMNATDP1MAPTPOLBHTT | |
| SCHEMBL5804956 | 0.91 | LMNA (0.46) | LMNAVCAM1TDP1MAPTPOLB | |
| SCHEMBL5803222 | 0.91 | LMNA (0.46) | LMNAVCAM1TDP1MAPTPOLB | |
| SCHEMBL5802841 | 0.88 | HTT (0.38) | LMNAVCAM1TDP1MAPTPOLB | |
| SCHEMBL5804422 | 0.87 | NPSR1 (0.44) | LMNATDP1MAPTPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006082452-A1 | OPTICALLY ACTIVE DIARYL ACETIC ACID DERIVATIVES AND PROCESS FOR THEIR PREPARATION | SANOFI-AVENTIS (FR) | 2006-08-10 | — | — | WO | disclosed |
| WO-2006082453-A1 | RACEMIC AND OPTICALLY ACTIVE 4-CHLORO-3-(5-CHLORO-3-ALKYL-2-OXO-2,3-DIHYDRO-1H-INDOL-3-YL)BENZOIC ACID DERIVATIVES AND THE PREPARATION THEREOF | SANOFI-AVENTIS (FR) | 2006-08-10 | — | — | WO | disclosed |
| WO-2006079857-A1 | DIARYL ACETIC ACID DERIVATIVES AND THE PREPARATION THEREOF | SANOFI-AVENTIS (FR) | 2006-08-03 | — | — | WO | disclosed |