Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | MPO | P05164 | 2/20 | 0.61 |
| ▸ | DRD4 | P21917 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3695539 | 1.00 | BCHE (0.77) | BCHEGAAMAPTSLC2A1KDM4E | |
| Hydrochloric Acid SCHEMBL9332806 | 0.98 | GAA (0.78) | BCHEGAAMAPTSLC2A1KDM4E | |
| SCHEMBL13960326 | 0.95 | BCHE (0.70) | BCHEGAAMAPTSLC2A1KDM4E | |
| SCHEMBL24142592 | 0.91 | BCHE (0.66) | BCHEGAAMAPTSLC2A1KDM4E | |
| SCHEMBL6540901 | 0.90 | BCHE (0.65) | BCHEGAAMAPTSLC2A1KDM4E | |
| SCHEMBL18122725 | 0.90 | OPRK1 (0.64) | BCHEGAAMAPTSLC2A1MPO | |
| SCHEMBL3272134 | 0.90 | GAA (0.91) | BCHEGAAMAPTKDM4EALDH1A1 | |
| SCHEMBL11881258 | 0.90 | GAA (0.91) | BCHEGAAMAPTKDM4EALDH1A1 | |
| SCHEMBL3866233 | 0.89 | SIGMAR1 (0.70) | BCHEMPO | |
| SCHEMBL3692847 | 0.89 | SIGMAR1 (0.70) | BCHEMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090240033-A1 | AFFINITY MATRIX LIBRARY AND ITS USE | LI RONGXIU | 2009-09-24 | — | — | US | claimed |
| EP-2834288-B1 | COLORED CHARGED SILSESQUIOXANES | BASF SE (DE) | 2017-04-26 | — | — | EP | disclosed |
| US-9228063-B2 | Colored charged silsesquioxanes | BASF SE (DE) | 2016-01-05 | — | — | US | disclosed |
| US-9228063-B2 | Colored charged silsesquioxanes | BASF SE (DE) | 2016-01-05 | — | — | US | disclosed |
| US-20140296518-A1 | Colored Charged Silsesquioxanes | BASF SE (DE) | 2014-10-02 | — | — | US | disclosed |
| WO-2013150444-A1 | COLORED CHARGED SILSESQUIOXANES | BASF SE (DE) | 2013-10-10 | — | — | WO | disclosed |
| US-8338611-B2 | Opioid receptor antagonists | ELI LILLY AND COMPANY (US) | 2012-12-25 | — | — | US | disclosed |
| US-8338611-B2 | Opioid receptor antagonists | ELI LILLY AND COMPANY (US) | 2012-12-25 | — | — | US | disclosed |
| US-8338611-B2 | Opioid receptor antagonists | ELI LILLY AND COMPANY (US) | 2012-12-25 | — | — | US | disclosed |
| EP-1735268-B1 | OPIOID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2012-02-15 | — | — | EP | disclosed |
| EP-0827746-A1 | Carbazole analogues as selective B3 adrenergic agonists | ELI LILLY AND COMPANY (US) | 1998-03-11 | — | — | EP | disclosed |
| WO-1997010887-A1 | NOVEL AFFINITY LIGANDS AND THEIR USE | NOVO NORDISK A/S (DK) | 1997-03-27 | — | — | WO | disclosed |
| US-RE35128-E | Method for the preparation of erythro vicinyl amino-alcohols | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1995-12-19 | — | — | US | disclosed |
| EP-0328251-B1 | 2-(2-Hydroxy-3-phenoxypropylamino)ethylphenoxyacetamides and processes and intermediates for their preparation | ICI PLC (GB) | 1994-04-13 | — | — | EP | disclosed |
| US-5189219-A | Reacting hydroxyl-protected cyanohydrin with grignard reagent, then with primary amine, reducing, deprotecting | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1993-02-23 | — | — | US | disclosed |
| EP-0492719-A1 | Method for the preparation of erythro vicinal amino-alcohols | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-07-01 | — | — | EP | disclosed |
| US-4999377-A | 2-(2-hydroxy-3-phenoxypropylamino)ethylphenoxyacetamide compounds; dietetics | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-03-12 | — | — | US | disclosed |
| CN-1046160-A | Thiophene derivant | ICI PLC (GB) | 1990-10-17 | — | — | CN | disclosed |
| EP-0386920-A2 | 2-Hydroxy-3-thienyloxypropylamino derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-09-12 | — | — | EP | disclosed |
| EP-0328251-A2 | 2-(2-Hydroxy-3-phenoxypropylamino)ethylphenoxyacetamides and processes and intermediates for their preparation | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-08-16 | — | — | EP | disclosed |