Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 9/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8805588 | 0.82 | MEN1 (0.43) | PPARGCYP3A4RXRAPPARACYP4F2 | |
| SCHEMBL1201522 | 0.81 | PPARG (0.53) | PPARGCYP3A4RXRAPPARACYP4F2 | |
| SCHEMBL1199906 | 0.81 | PPARG (0.53) | PPARGCYP3A4RXRAPPARACYP4F2 | |
| SCHEMBL943063 | 0.79 | PPARG (0.58) | PPARGCYP3A4RXRAPOLBALDH1A1 | |
| SCHEMBL5805165 | 0.78 | PPARG (0.48) | PPARGCYP3A4RXRAPPARACYP4F2 | |
| SCHEMBL1162595 | 0.78 | LMNA (0.63) | PPARGCYP3A4RXRAPPARACYP4F2 | |
| SCHEMBL18015059 | 0.77 | PPARG (0.57) | PPARGCYP3A4RXRAPOLBLMNA | |
| SCHEMBL6509355 | 0.77 | PPARG (0.46) | PPARGCYP3A4RXRAPPARACYP4F2 | |
| SCHEMBL6509358 | 0.77 | PPARG (0.46) | PPARGCYP3A4RXRAPPARACYP4F2 | |
| SCHEMBL24209462 | 0.76 | PPARG (0.54) | PPARGCYP3A4RXRAPPARACYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006082495-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | RANBAXY LABORATORIES LIMITED (IN) | 2006-08-10 | — | — | WO | disclosed |