Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 11/20 | 0.38 |
| ▸ | PPARD | Q03181 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509355 | 1.00 | PPARG (0.46) | PPARGCYP3A4RXRACYP4F2CYP4A11 | |
| SCHEMBL1201522 | 0.81 | PPARG (0.53) | PPARGCYP3A4RXRACYP4F2CYP4A11 | |
| SCHEMBL1199906 | 0.81 | PPARG (0.53) | PPARGCYP3A4RXRACYP4F2CYP4A11 | |
| SCHEMBL6505868 | 0.78 | PPARG (0.52) | PPARGPPARA | |
| SCHEMBL5802964 | 0.77 | PPARG (0.51) | PPARGCYP3A4RXRACYP4F2CYP4A11 | |
| SCHEMBL24209462 | 0.77 | PPARG (0.54) | PPARGCYP3A4RXRACYP4F2CYP4A11 | |
| SCHEMBL943063 | 0.74 | PPARG (0.58) | PPARGCYP3A4RXRAALDH1A1POLB | |
| SCHEMBL1162595 | 0.73 | LMNA (0.63) | PPARGCYP3A4RXRACYP4F2CYP4A11 | |
| SCHEMBL6383438 | 0.73 | PPARG (0.47) | PPARGCYP3A4RXRACYP4F2CYP4A11 | |
| SCHEMBL6383648 | 0.73 | PPARG (0.47) | PPARGCYP3A4RXRACYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |