⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10531966 | 0.89 | — | — | |
| SCHEMBL9785460 | 0.87 | — | — | |
| SCHEMBL151989 | 0.86 | — | — | |
| SCHEMBL9766066 | 0.80 | POLB (0.36) | — | |
| SCHEMBL9504446 | 0.79 | — | — | |
| SCHEMBL14299607 | 0.77 | — | — | |
| SCHEMBL17747969 | 0.77 | GABRA1 (0.34) | — | |
| SCHEMBL358421 | 0.77 | TSHR (0.32) | — | |
| SCHEMBL9810488 | 0.77 | KDM4E (0.34) | — | |
| SCHEMBL10341834 | 0.77 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828739-B1 | BICYCLIC AMINES AS INSECTICIDES | SYNGENTA LTD (GB) | 2002-09-11 | — | — | EP | claimed |
| US-5922732-A | INSECTICIDES, MITICIDES AND NEMATOCIDES | ZENECA LIMITED (GB) | 1999-07-13 | — | — | US | claimed |
| EP-0281439-B1 | ESTERS OF CYCLOPROPANECARBOXYLIC ACIDS RELATED TO PYRETHRIC ACID, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PARASITICIDES | ROUSSEL-UCLAF (FR) | 1991-06-12 | — | — | EP | claimed |
| US-4939172-A | Novel cyclopropane carboxylates | ROUSSEL UCLAF (FR) | 1990-07-03 | — | — | US | claimed |
| EP-0295839-A2 | Pyrimidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-21 | — | — | EP | claimed |
| US-4762835-A | INSECTICIDES, MITICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-09 | — | — | US | claimed |
| EP-0227415-A2 | Pyrimidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-07-01 | — | — | EP | claimed |
| EP-0031199-B1 | SUBSTITUTED BENZYL ESTERS OF CYCLOPROPANE CARBOXYLIC ACIDS AND THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND METHODS OF COMBATING INSECT PESTS THEREWITH, AND SUBSTITUTED BENZYL ALCOHOLS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-12-14 | — | — | EP | claimed |
| US-4405640-A | Substituted fluorobenzyl cyclopropane carboxylates useful as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-09-20 | — | — | US | claimed |
| EP-0031199-A1 | Substituted benzyl esters of cyclopropane carboxylic acids and their preparation, compositions containing them and methods of combating insect pests therewith, and substituted benzyl alcohols | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-07-01 | — | — | EP | claimed |
| EP-2508509-B1 | PROCESS FOR PREPARATION OF (Z)-CYANOALKENYLCYCLOPROPANECARBOXYLIC ACID COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2016-08-17 | — | — | EP | disclosed |
| US-20160050930-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS | SYNGENTA LIMITED (UK) | 2016-02-25 | — | — | US | disclosed |
| EP-2978316-A1 | METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS | Syngenta Participations AG (CH) | 2016-02-03 | — | — | EP | disclosed |
| EP-2125708-B1 | CYCLOPROPANE CARBOXYLIC ESTER COMPOUNDS AND THEIR USE IN PEST CONTROL | SUMITOMO CHEMICAL CO (JP) | 2015-06-17 | — | — | EP | disclosed |
| EP-2540701-B1 | PROCESS FOR PRODUCTION OF CYCLOPROPANECARBOXYLIC ACID ESTER COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2014-10-22 | — | — | EP | disclosed |
| US-4760143-A | Contining pyrimidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-07-26 | — | — | US | disclosed |
| EP-0227415-A2 | Pyrimidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-07-01 | — | — | EP | disclosed |
| US-4661488-A | Pyrimidine substituted-2,2-dimethylcyclopropane carboxylates useful for combating insect and acarine pests at a locus | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-04-28 | — | — | US | disclosed |
| EP-0181284-A1 | Amino acid esters | SANDOZ AG (CH) | 1986-05-14 | — | — | EP | disclosed |
| EP-0162538-A2 | Cyclopropane derivates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-11-27 | — | — | EP | disclosed |