SCHEMBL9810488

SCHEMBL9810488

C=CCc1c(F)c(F)c(C)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34
NPSR1 Q6W5P4 1/20 0.32
IMPDH2 P12268 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10531966 0.87
SCHEMBL151989 0.84
SCHEMBL28781585 0.82 KDM4E (0.31) KDM4EALDH1A1MAPTHPGDALOX15
Water SCHEMBL28929410 0.81
SCHEMBL14299607 0.80
SCHEMBL14406600 0.78 KDM4E (0.31) KDM4EALDH1A1MAPTHPGDALOX15
SCHEMBL9504446 0.77
SCHEMBL580325 0.77
SCHEMBL3418214 0.76 TSHR (0.31)
SCHEMBL8190670 0.75 ALDH1A1 (0.39) KDM4EALDH1A1MAPTHPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0281439-B1 ESTERS OF CYCLOPROPANECARBOXYLIC ACIDS RELATED TO PYRETHRIC ACID, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PARASITICIDES ROUSSEL-UCLAF (FR) 1991-06-12 EP claimed
EP-3524646-B1 IONIC COMPOUND, COATING COMPOSITION COMPRISING SAME, AND ORGANIC LIGHT-EMITTING DIODE LG CHEMICAL LTD (KR) 2021-07-21 EP disclosed
EP-3524646-A1 IONIC COMPOUND, COATING COMPOSITION COMPRISING SAME, AND ORGANIC LIGHT-EMITTING DIODE LG Chem, Ltd. (KR) 2019-08-14 EP disclosed
US-20160050930-A1 METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS SYNGENTA LIMITED (UK) 2016-02-25 US disclosed
EP-2978316-A1 METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS Syngenta Participations AG (CH) 2016-02-03 EP disclosed
WO-2014154488-A1 METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS SYNGENTA PARTICIPATIONS AG (CH) 2014-10-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160050930-A1 METHODS OF CONTROLLING NEONICOTINOID RESISTANT PESTS DDT, CRY1, NISCH KDM4E 2289/4885ALDH1A1 2576/4885MAPT 4375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.