Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.46 |
| ▸ | MEN1 | O00255 | 11/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CASR | P41180 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL580382 | 1.00 | KMT2A (0.46) | KMT2AMEN1OPRD1OPRM1NSD2 | |
| SCHEMBL3687851 | 0.84 | KMT2A (0.48) | KMT2AMEN1OPRD1OPRM1NSD2 | |
| SCHEMBL580432 | 0.82 | SLC6A4 (0.44) | KMT2AMEN1OPRM1OPRK1LMNA | |
| SCHEMBL5224091 | 0.82 | SLC6A4 (0.44) | KMT2AMEN1OPRM1OPRK1LMNA | |
| SCHEMBL577829 | 0.82 | SLC6A4 (0.44) | KMT2AMEN1OPRM1OPRK1LMNA | |
| SCHEMBL579703 | 0.82 | CYP1A2 (0.43) | KMT2AMEN1CYP3A4CASRCYP1A2 | |
| SCHEMBL580496 | 0.82 | CYP1A2 (0.43) | KMT2AMEN1CYP3A4CASRCYP1A2 | |
| Hydrochloric Acid SCHEMBL579534 | 0.81 | CYP3A4 (0.44) | KMT2AMEN1OPRM1OPRK1LMNA | |
| SCHEMBL580162 | 0.81 | MEN1 (0.47) | KMT2AMEN1OPRD1OPRM1NSD2 | |
| Hydrochloric Acid SCHEMBL579705 | 0.81 | CYP3A4 (0.44) | KMT2AMEN1OPRM1OPRK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633695-B1 | SMOOTH MUSCLE SPASMOLYTIC AGENTS | BRIDGE PHARMA INC (US) | 2012-02-15 | — | — | EP | disclosed |
| EP-1633695-A4 | SMOOTH MUSCLE SPASMOLYTIC AGENTS | BRIDGE PHARMA INC (US) | 2007-12-12 | — | — | EP | disclosed |
| US-7141696-B2 | Smooth muscle spasmolytic agents | BRIDGE PHARMA, INC. (US) | 2006-11-28 | — | — | US | disclosed |
| EP-1633695-A2 | SMOOTH MUSCLE SPASMOLYTIC AGENTS | Bridge Pharma, Inc. (US) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004105692-A2 | SMOOTH MUSCLE SPASMOLYTIC AGENTS | BRIDGE PHARMA, INC. (US) | 2004-12-09 | — | — | WO | disclosed |
| US-20040248987-A1 | Smooth muscle spasmolytic agents | BRIDGE PHARMA, INC. | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248987-A1 | Smooth muscle spasmolytic agents | MYLK, TNNC1, MYLK2 | KMT2A 1676/4885MEN1 2669/4885OPRD1 818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.