Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 20/20 | 0.56 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.56 |
| ▸ | DRD5 | P21918 | 2/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5807534 | 0.91 | GALR3 (0.60) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL5807446 | 0.89 | GALR3 (0.52) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL5807766 | 0.86 | GALR3 (0.66) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL5807322 | 0.84 | GALR3 (0.55) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL5807393 | 0.81 | GALR3 (0.71) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL8244135 | 0.80 | GALR3 (0.76) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL5805468 | 0.79 | GALR3 (0.78) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL915968 | 0.76 | GALR3 (0.83) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL915969 | 0.76 | GALR3 (0.83) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL5356928 | 0.75 | GALR3 (0.81) | GALR3HTR4DRD5ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006083538-A1 | AMINOALKYLPHENYL INDOLONE DERIVATIVES | H. LUNDBECK A/S (DK) | 2006-08-10 | — | — | WO | disclosed |
| US-20060173192-A1 | Aminoalkylphenyl indolone derivatives | H. LUNDBECK A/S | 2006-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173192-A1 | Aminoalkylphenyl indolone derivatives | GALR3, HTR3E, HTR3C | GALR3 1/4885HTR4 14/4885DRD5 333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.