Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | POLB | P06746 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | PKM | P14618 | 4/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | TGM2 | P21980 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5803748 | 0.93 | KMT2A (0.58) | KMT2AALDH1A1POLBMAPTPKM | |
| SCHEMBL19079794 | 0.76 | NPSR1 (0.68) | KMT2AALDH1A1POLBMAPTPKM | |
| SCHEMBL6848893 | 0.73 | KMT2A (0.66) | KMT2AALDH1A1POLBMAPTPKM | |
| SCHEMBL5807546 | 0.71 | NPSR1 (0.70) | KMT2AALDH1A1POLBMAPTPKM | |
| SCHEMBL6034409 | 0.67 | TGM2 (1.00) | ALDH1A1MAPTNPSR1TGM2TP53 | |
| SCHEMBL6034354 | 0.66 | TGM2 (1.00) | ALDH1A1MAPTTGM2HTT | |
| SCHEMBL6034215 | 0.64 | TP53 (0.72) | KMT2AALDH1A1MAPTNPSR1MEN1 | |
| SCHEMBL6037616 | 0.63 | TGM2 (1.00) | TGM2 | |
| SCHEMBL6033353 | 0.62 | TGM2 (0.71) | KMT2AALDH1A1MAPTHSD17B10TSHR | |
| SCHEMBL6037657 | 0.61 | TGM2 (1.00) | TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |