Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.62 |
| ▸ | TGM2 | P21980 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAPDH | P04406 | 1/20 | 0.53 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19079794 | 0.82 | NPSR1 (0.68) | KMT2AMEN1NPSR1TGM2KDM4E | |
| SCHEMBL5807546 | 0.76 | NPSR1 (0.70) | KMT2AMEN1NPSR1TGM2KDM4E | |
| SCHEMBL6034409 | 0.74 | TGM2 (1.00) | NPSR1TGM2ALDH1A1HTTLMNA | |
| SCHEMBL5803743 | 0.73 | KMT2A (0.58) | KMT2AMEN1NPSR1TGM2KDM4E | |
| SCHEMBL5803748 | 0.73 | KMT2A (0.58) | KMT2AMEN1NPSR1TGM2KDM4E | |
| SCHEMBL6037616 | 0.70 | TGM2 (1.00) | TGM2 | |
| SCHEMBL6034354 | 0.69 | TGM2 (1.00) | TGM2ALDH1A1HTTMAPT | |
| SCHEMBL6037657 | 0.67 | TGM2 (1.00) | TGM2 | |
| SCHEMBL6034215 | 0.67 | TP53 (0.72) | KMT2AMEN1NPSR1TGM2KDM4E | |
| SCHEMBL6033974 | 0.67 | TGM2 (0.78) | TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011020849-A1 | CYTOHESIN INHIBITORS | RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITÄT (DE) | 2011-02-24 | — | — | WO | disclosed |
| EP-2286808-A1 | Cytohesin inhibitors | Rheinische Friedrich-Wilhelms Universität (DE) | 2011-02-23 | — | — | EP | disclosed |