Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | FLT3 | P36888 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | GFER | P55789 | 1/20 | 0.67 |
| ▸ | CDK2 | P24941 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 5/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804131 | 0.86 | KDM4E (0.75) | KDM4EMAPK1FLT3ALDH1A1SMN1; SMN2 | |
| SCHEMBL31562921 | 0.86 | KDM4E (0.75) | KDM4EMAPK1FLT3ALDH1A1SMN1; SMN2 | |
| SCHEMBL8289412 | 0.86 | KDM4E (1.00) | KDM4EMAPK1FLT3ALDH1A1SMN1; SMN2 | |
| SCHEMBL5805621 | 0.83 | ALDH1A1 (0.72) | KDM4EMAPK1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL1007246 | 0.83 | FLT3 (0.75) | KDM4EMAPK1FLT3ALDH1A1SMN1; SMN2 | |
| SCHEMBL5453467 | 0.83 | FLT3 (1.00) | KDM4EMAPK1FLT3ALDH1A1SMN1; SMN2 | |
| SCHEMBL3453042 | 0.83 | FLT3 (0.75) | KDM4EMAPK1FLT3ALDH1A1SMN1; SMN2 | |
| SCHEMBL4135422 | 0.83 | HPGD (0.83) | KDM4EMAPK1FLT3ALDH1A1SMN1; SMN2 | |
| SCHEMBL8289831 | 0.82 | ALDH1A1 (0.78) | KDM4EMAPK1FLT3ALDH1A1SMN1; SMN2 | |
| SCHEMBL8288772 | 0.82 | KDM4E (0.74) | KDM4EMAPK1FLT3ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |