Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10789270 | 0.83 | HSD17B10 (0.53) | HSD17B10KMT2AMEN1LMNAGAA | |
| SCHEMBL19862412 | 0.82 | HSD17B10 (0.56) | HSD17B10KMT2AMEN1LMNAGAA | |
| SCHEMBL17125223 | 0.82 | HSD17B10 (0.60) | HSD17B10KMT2AMEN1LMNATSHR | |
| SCHEMBL10914645 | 0.81 | AKR1C3 (0.52) | KMT2AMEN1LMNAGAAMAPT | |
| SCHEMBL4658268 | 0.81 | LMNA (0.48) | HSD17B10KMT2AMEN1LMNAGAA | |
| SCHEMBL3584977 | 0.79 | ALDH1A1 (0.50) | KMT2AMEN1LMNAMAPTTP53 | |
| SCHEMBL3584980 | 0.79 | ALDH1A1 (0.50) | KMT2AMEN1LMNAMAPTTP53 | |
| SCHEMBL2130850 | 0.79 | ALDH1A1 (0.50) | KMT2AMEN1LMNAMAPTTP53 | |
| SCHEMBL17165018 | 0.79 | ALDH1A1 (0.50) | KMT2AMEN1LMNAMAPTTP53 | |
| SCHEMBL17165030 | 0.79 | MEN1 (0.55) | KMT2AMEN1LMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006079857-A1 | DIARYL ACETIC ACID DERIVATIVES AND THE PREPARATION THEREOF | SANOFI-AVENTIS (FR) | 2006-08-03 | — | — | WO | disclosed |
| EP-0056144-A1 | Carboxylic acid derivatives, their preparation and use as pharmaceuticals | Dr. Karl Thomae GmbH (DE) | 1982-07-21 | — | — | EP | disclosed |