Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 3/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804209 | 1.00 | FBP1 (0.48) | FBP1AKR1C3MCL1ALDH1A1TSHR | |
| SCHEMBL9015118 | 0.79 | MCL1 (0.52) | FBP1AKR1C3MCL1ALDH1A1TSHR | |
| SCHEMBL2000510 | 0.79 | MCL1 (0.52) | FBP1AKR1C3MCL1ALDH1A1TSHR | |
| SCHEMBL143642 | 0.77 | ALDH1A1 (0.54) | FBP1AKR1C3MCL1ALDH1A1TSHR | |
| SCHEMBL143643 | 0.77 | ALDH1A1 (0.54) | FBP1AKR1C3MCL1ALDH1A1TSHR | |
| SCHEMBL4788817 | 0.76 | ALDH1A1 (0.46) | FBP1AKR1C3MCL1ALDH1A1TSHR | |
| SCHEMBL197670 | 0.76 | ALDH1A1 (0.46) | FBP1AKR1C3MCL1ALDH1A1TSHR | |
| SCHEMBL5386095 | 0.74 | MAPT (0.58) | AKR1C3MCL1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL5386096 | 0.74 | MAPT (0.58) | AKR1C3MCL1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL4788053 | 0.73 | ALDH1A1 (0.43) | FBP1AKR1C3MCL1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |