Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14279165 | 0.76 | HPGD (0.51) | ALDH1A1TDP1POLBHPGDHSD17B10 | |
| SCHEMBL11749078 | 0.76 | EPHX2 (0.58) | ALDH1A1EPHX2TDP1POLBHPGD | |
| SCHEMBL1106990 | 0.76 | ALDH1A1 (0.60) | ALDH1A1EPHX2TDP1POLBHPGD | |
| SCHEMBL2638805 | 0.76 | ALDH1A1 (0.68) | ALDH1A1EPHX2TDP1POLBHPGD | |
| SCHEMBL24575916 | 0.75 | EPHX2 (0.83) | ALDH1A1EPHX2TDP1POLBHPGD | |
| SCHEMBL14694017 | 0.75 | ALDH1A1 (0.66) | ALDH1A1EPHX2TDP1POLBHPGD | |
| SCHEMBL18415483 | 0.75 | POLB (0.77) | ALDH1A1EPHX2TDP1POLBHPGD | |
| SCHEMBL1455280 | 0.73 | ALDH1A1 (0.64) | ALDH1A1EPHX2TDP1POLBHPGD | |
| SCHEMBL1694937 | 0.73 | ALDH1A1 (0.64) | ALDH1A1EPHX2TDP1POLBHPGD | |
| SCHEMBL29410065 | 0.73 | ALDH1A1 (0.74) | ALDH1A1EPHX2TDP1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |