Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14279166 | 0.83 | KDM1A (0.56) | TP53KMT2A | |
| SCHEMBL2245712 | 0.82 | ADAMTS5 (0.56) | HPGDALDH1A1LMNATDP1NPSR1 | |
| SCHEMBL14279161 | 0.80 | HPGD (0.61) | HPGDALDH1A1LMNANPSR1POLB | |
| SCHEMBL1490952 | 0.78 | HPGD (0.76) | HPGDALDH1A1LMNATDP1NPSR1 | |
| SCHEMBL14264750 | 0.78 | ALDH1A1 (0.57) | HPGDALDH1A1LMNATDP1RECQL | |
| SCHEMBL5804331 | 0.76 | ALDH1A1 (0.51) | HPGDALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL2330374 | 0.75 | CTRB1 (0.51) | HPGDTDP1 | |
| SCHEMBL2330376 | 0.75 | CTRB1 (0.51) | HPGDTDP1 | |
| SCHEMBL2330371 | 0.75 | CTRB1 (0.51) | HPGDTDP1 | |
| SCHEMBL14279164 | 0.75 | KMT2A (0.54) | HPGDALDH1A1LMNATDP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7320755-B2 | Method of preparing ligands for hydrophobic interaction chromatography | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2008-01-22 | — | — | US | disclosed |
| US-7320755-B2 | Method of preparing ligands for hydrophobic interaction chromatography | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2008-01-22 | — | — | US | disclosed |